![]() Sample Type: Cells dissociated from zebrafish testicle. The kit is suitable for specifically measuring global histone H3 acetylation using a variety of mammalian cells including fresh and frozen tissues, and cultured adherent and suspension cells. The kit is ready-to-use and provides all the essential components needed to carry out a successful assay experiment. Histone H3 Acetylation Assay Kit (ab115102) allows the user to measure global acetylation of histone H3 at tremendously fast speeds and consistency, superior and safer than all other current methods. ![]() An imbalance in the equilibrium of histone acetylation has been associated with tumorigenesis and cancer progression. Histone acetylation is tightly involved in cell cycle regulation, cell proliferation and apoptosis. HATs (histone acetyltransferases) and HDACs (histone deacetylases) play a critical role in controlling histone H3 actylation. Acetylation of histones such histone H3 has been involved in the regulation of chromatin structure and the recruitment of transcription factors to gene promoters.
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